The Pennsylvania State university college of medicine 1991 Bernard B. Brodie lecture : insights into deuterium isotope effects on the metabolism of steroid hormones and foreign compounds by cytochrome P-450 enzymesGILLETTE, J. R.Life sciences (1973). 1991, Vol 49, Num 1, pp 1-14, issn 0024-3205Article

Keynote address: man, mice, microsomes, metabolites, and mathematics 40 years after the revolutionGILLETTE, J. R.Drug metabolism reviews (Softcover ed.). 1995, Vol 27, Num 1-2, pp 1-44, issn 0360-2532Conference Paper

Pharmacokinetic procedures for the estimation of organ clearances for the formation of short-lived metabolites: acetaminophen-induced glutathione depletion in hamster liverCHEN, R; GILLETTE, J. R.Drug metabolism and disposition. 1988, Vol 16, Num 3, pp 373-385, issn 0090-9556Article

Theoretical kinetics of sequential metabolism in vitro : study of the formation of 16α-hydroxyandrostenedione from testosterone by purified rat P450 2C11SUGIYAMA, K; NAGATA, K; GILLETTE, J. R et al.Drug metabolism and disposition. 1994, Vol 22, Num 4, pp 584-591, issn 0090-9556Article

An immunochemical approach to investigating the mechanism of halothane-induced hepatotoxicitySATOH, H; DAVIES, H. W; TAKEMURA, T et al.Progress in drug metabolism. 1987, Vol 10, pp 187-206, issn 0364-8974Article

The mechanism of formation of ο-bromophenol from bromobenzeneMONKS, T. J; LAU, S. S; POHL, L. R et al.Drug metabolism and disposition. 1984, Vol 12, Num 2, pp 193-198, issn 0090-9556Article

12α-hydroxytestosterone. A hitherto unidentified testosterone metabolite produced by cytochrome P-450 2A2SMITH, S. J; KORZEKWA, K. R; AOYAMA, T et al.Drug metabolism and disposition. 1992, Vol 20, Num 4, pp 566-571, issn 0090-9556Article

Isotope effect studies on the mechanism of the cytochrome P-450IIA1-catalyzed formation of Δ⁶-testosterone from testosteroneKORZEKWA, K. R; TRAGER, W. F; NAGATA, K et al.Drug metabolism and disposition. 1990, Vol 18, Num 6, pp 974-979, issn 0090-9556, 6 p.Article

Theory for the observed isotope effects from enzymatic systems that form multiple products via branched reaction pathways: cytochrome P-450KORZEKWA, K. R; TRAGER, W. F; GILLETTE, J. R et al.Biochemistry (Easton). 1989, Vol 28, Num 23, pp 9012-9018, issn 0006-2960Article

Glutathione conjugates of 2-bromohydroquinone are nephrotoxicMONKS, T. J; LAU, S. S; HIGHET, R. J et al.Drug metabolism and disposition. 1985, Vol 13, Num 5, pp 553-559, issn 0090-9556Article

Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated miceNAGATA, K; MARTIN, B. M; GILLETTE, J. R et al.Drug metabolism and disposition. 1990, Vol 18, Num 5, pp 557-564, issn 0090-9556, 8 p.Article

The formation of a glutathione conjugate derived from propranololSASAME, H. A; LIBERATO, D. J; GILLETTE, J. R et al.Drug metabolism and disposition. 1987, Vol 15, Num 3, pp 349-355, issn 0090-9556Article

An unusual metabolite of testosterone: 17β-hydroxy-4,6-androstadiene-3-oneNAGATA, K; LIBERATO, D. J; GILLETTE, J. R et al.Drug metabolism and disposition. 1986, Vol 14, Num 5, pp 559-565, issn 0090-9556Article

Detection and half-life of bromobenzene-3,4-oxide in bloodLAU, S. S; MONKS, T. J; GREENE, K. E et al.Xenobiotica (London. Print). 1984, Vol 14, Num 7, pp 539-543, issn 0049-8254Article

Social monogamy in a territorial salamanderGILLETTE, J. R; JAEGER, R. G; PETERSON, M. G et al.Animal behaviour. 2000, Vol 59, pp 1241-1250, issn 0003-3472, 6Article

Theoretical studies on the mechanism of conversion of androgens to estrogens by aromataseKORZEKWA, K. R; TRAGER, W. F; SMITH, S. J et al.Biochemistry (Easton). 1991, Vol 30, Num 25, pp 6155-6162, issn 0006-2960Article

Identification of 2-bromohydroquinone as a metabolite of bromobenzene and o-bromophenol: implications for bromobenzene-induced nephrotoxicityLAU, S. S; MONKS, T. J; GILLETTE, J. R et al.The Journal of pharmacology and experimental therapeutics. 1984, Vol 230, Num 2, pp 360-366, issn 0022-3565Article

Multiple reactive metabolites derived from bromobenzeneLAU, S. S; MONKS, T. J; GILLETTE, J. R et al.Drug metabolism and disposition. 1984, Vol 12, Num 3, pp 291-296, issn 0090-9556Article

Deuterium isotope effects on A-ring and D-ring metabolism of testosterone by CYP2C11 : evidence for dissociation of activated enzyme-substrate complexesDARBYSHIRE, J. F; GILLETTE, J. R; NAGATA, K et al.Biochemistry (Easton). 1994, Vol 33, Num 10, pp 2938-2944, issn 0006-2960Article

Theory for the observed isotope effects on the formation of multiple products by different kinetic mechanisms of cytochrome P450 enzymesGILLETTE, J. R; DARBYSHIRE, J. F; SUGIYAMA, K et al.Biochemistry (Easton). 1994, Vol 33, Num 10, pp 2927-2937, issn 0006-2960Article

Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytesSATOH, H; FUKUDA, Y; ANDERSON, D. K et al.The Journal of pharmacology and experimental therapeutics. 1985, Vol 233, Num 3, pp 857-862, issn 0022-3565Article

Diffusion of reactive metabolites out of hepatocytes: studies with bromobenzeneMONKS, T. J; LAU, S. S; GILLETTE, J. R et al.The Journal of pharmacology and experimental therapeutics. 1984, Vol 228, Num 2, pp 393-399, issn 0022-3565Article

The role of ortho-bromophenol in the nephrotoxicity of bromobenzene in ratsLAU, S. S; MONKS, T. J; GREENE, K. E et al.Toxicology and applied pharmacology. 1984, Vol 72, Num 3, pp 539-549, issn 0041-008XArticle

Isotope effect studies on the cytochrome P450 enzymesKORZEKWA, K. R; GILLETTE, J. R; TRAGER, W. F et al.Drug metabolism reviews (Softcover ed.). 1995, Vol 27, Num 1-2, pp 45-59, issn 0360-2532Conference Paper

Mouse pulmonary cytochrome P-450 naphtalene hydroxylase : cDNA cloning sequence, and expression in Saccharomyces cerevisiaeRITTER, J. K; OWENS, I. S; NEGISHI, M et al.Biochemistry (Easton). 1991, Vol 30, Num 48, pp 11430-11437, issn 0006-2960Article